One step process for preparing cross-linked poly-.beta.-alanine

Details One step process for preparing cross-linked poly-.beta.-alanine One step process for preparing cross-linked poly-.beta.-alanine

1990-06-14

1991-12-31

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

428402, 5263031, 526306, 526307, 5263075, 526203, 526263, 526281, 514952, A61K 916, C08F 2056

Patent

active

050770586

ABSTRACT:
A one-step process for preparing cross-linked poly-.beta.-alanine as microspheres having narrow size distribution comprises polymerizing acrylamide with a polyfunctional compound copolymerizable with acrylamide (with the polyfunctional compound also acting as the cross-linking agent) in an organic solvent or a mixtured such solvents in the presence of an ionic polymerization initiator and a suspension agent. The resulting microspheres may be impregnated with a pharmaceutically or cosmetically active substance.

REFERENCES:
patent: 4734286 (1988-03-01), Mahieu et al.
patent: 4803252 (1989-02-01), Kida et al.

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