One-stage prothrombin assay and compositions useful therein

Details One-stage prothrombin assay and compositions useful therein One-stage prothrombin assay and compositions useful therein

1979-01-08

1981-09-15

Serwin, R. E.

Chemistry: physical processes

Physical processes

Crystallization

23918, 252408, G01N 3386

Patent

active

042894980

ABSTRACT:
A one-stage prothrombin assay which measures the exponential rate of thrombin production in thromboplastin-treated, recalcified plasma. A serum reagent reduces the lag time before thrombin production substantially to zero for both normal and abnormal plasma, thus allowing measurements to be made in just a few minutes.

REFERENCES:
patent: 3486981 (1969-12-01), Speck
patent: 3884896 (1975-05-01), Birger et al.
patent: 3886136 (1975-05-01), Claeson et al.
patent: 4047890 (1977-09-01), Eichelberger et al.
patent: 4061625 (1977-12-01), Thuresson
H. C. Hemker, et al., Thrombosis et Diathesis Haemorrhagica 13, 156-175 (1965).

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