One-pot process for the preparation of .alpha.-L-aspartyl-L-phen

Details One-pot process for the preparation of .alpha.-L-aspartyl-L-phen One-pot process for the preparation of .alpha.-L-aspartyl-L-phen

1990-07-03

1991-10-01

Gray, Bruce

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 41, C07C22900

Patent

active

050535323

ABSTRACT:
A one-pot process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride is disclosed (.alpha.-APM(HCl)). .alpha.-APM(HCl) is an intermediate in the preparation of aspartame.

REFERENCES:
patent: 4745210 (1988-05-01), Mita et al.
patent: 4760164 (1988-07-01), Park et al.
patent: 4810816 (1989-03-01), Tsuji et al.
patent: 4820861 (1989-04-01), Yukawa et al.
patent: 4946988 (1990-08-01), Hill et al.

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