One-pot process for the preparation of 3-quinolonecarboxylic aci

Details One-pot process for the preparation of 3-quinolonecarboxylic aci One-pot process for the preparation of 3-quinolonecarboxylic aci

1994-12-02

1997-06-17

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546156, 546157, C07D215227, C07D21538

Patent

active

056398867

ABSTRACT:
The present invention relates to a one-pot process for the preparation of 7-heterocyclyl-substituted 3-quinolonecarboxylic acid derivatives. They possess a strong anti-microbial effect. They include active compounds such as, for example, ofloxacin, ciprofloxacin or enrofloxacin.

REFERENCES:
patent: 4780468 (1988-10-01), Bridges et al.
patent: 4894458 (1990-01-01), Masuzawa et al.
patent: 4990517 (1991-02-01), Petersen et al.
patent: 5037834 (1991-08-01), Brighty et al.
patent: 5468861 (1995-11-01), Petersen
patent: 5496947 (1996-03-01), Yoon
patent: 5498615 (1996-03-01), Kim
Grohe, "Syntheses von 4-Chinolon-3-carbonsauren", Liebigs Ann Chem, vol. 1987, No. 1, pp. 29-37, 1987.

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