One-component tissue adhesive and a process for the production t

Details One-component tissue adhesive and a process for the production t One-component tissue adhesive and a process for the production t

1992-11-30

1995-04-18

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

514 2, 514 8, 514802, 514822, 424530, A61K 3754, A61K 3702

Patent

active

054076714

ABSTRACT:
A description is given of a one-component tissue adhesive containing, in aqueous solution, fibrinogen, F XIII, a thrombin inhibitor, prothrombin factors, calcium ions and, where appropriate, a plasmin inhibitor and of a process for the production thereof.
This adhesive can be reconstituted from a freeze-dried form with water. It can contain all active substances in pasteurized form and is then free of the risk of transmission of hepatitis and HTLV III.

REFERENCES:
patent: 4297344 (1981-10-01), Schwinn et al.
patent: 4298598 (1981-11-01), Schwarz et al.
patent: 4327086 (1982-04-01), Fukushim et al.
patent: 4377572 (1983-03-01), Schwarz et al.
patent: 4411794 (1983-10-01), Schwinn et al.
patent: 4414976 (1983-11-01), Schwarz et al.
patent: 4427650 (1984-01-01), Stroetmann
patent: 4465623 (1984-08-01), Chanas et al.
patent: 4650678 (1987-03-01), Fuhge et al.
Bang, et al., Thrombosis and Bleeding Disorders, Academic Press (1971), p. 236.

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