Ondansetron freeze-dried dosage form compositions for oral admin

Details Ondansetron freeze-dried dosage form compositions for oral admin Ondansetron freeze-dried dosage form compositions for oral admin

1999-01-28

2000-05-16

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31415

Patent

active

060638028

ABSTRACT:
The invention relates to a freeze-dried dosage form for oral administration capable of being rapidly disintegrated in the mouth comprising ondansetron in the form of its free base or a pharmaceutically acceptable solvate thereof and one or more pharmaceutically acceptable excipients. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine (5HT) at 5HT.sub.3 receptors are also described.

REFERENCES:
patent: 4754597 (1988-07-01), Buxton et al.
patent: 4929632 (1990-05-01), Tyers et al.
patent: 5046618 (1991-09-01), Wood
patent: 5188825 (1993-02-01), Iles et al.
patent: 5288497 (1994-02-01), Stanley et al.
patent: 5785989 (1998-07-01), Stanley et al.
Remington's Pharmaceutical Sciences, 16th ed. pp 1111 and 1225-1227, 1980.

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