Oncornavirus vaccines and feline alpha-type interferon

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits

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424 89, 424 93, C12N 706, A61K 3921

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active

048617202

ABSTRACT:
Retroviral vaccines are provided comprising incompetent retroviruses containing defective RNA produced by growing viral transformed cells in the presence of interferon. The resulting defective viruses by themselves or in combination with interferon can be used as vaccines for immunizing viral sensitive hosts against infection. A novel feline interferon is produced in culture with cells infected with the defective non-infectious retroviruses.

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patent: 4699785 (1987-10-01), Pedersen
Chemical Abstracts, vol. 103, Abstract No. 140019h, 1983.
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Chemical Abstracts, vol. 77, Abstract No. 86507v, 1972.
Chemical Abstracts, vol. 99, Abstract No. 156594b, 1983.

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