Oncoprotein protein kinase

Details Oncoprotein protein kinase Oncoprotein protein kinase

2005-03-08

2005-03-08

Patterson, Jr., Charles L. (Department: 1652)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S094100, C524S002000, C524S044000

Reexamination Certificate

active

06863888

ABSTRACT:
An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.

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