Onco-fetal specific monoclonal antibodies, methods of preparatio

Details Onco-fetal specific monoclonal antibodies, methods of preparatio Onco-fetal specific monoclonal antibodies, methods of preparatio

1984-11-21

1987-08-11

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

4351722, 435948, 43524047, 436513, 436548, 436804, 436813, 530387, 935103, 935104, 935110, G01N 3353, G01N 33574

Patent

active

046861807

ABSTRACT:
A process of preparing a hybridoma secreting oncofetal-specific monoclonal antibodies, which comprises: (a) immunizing an animal with immunizing amounts of a non-proliferating syngeneic mid-gestation fetal cell preparation; (b) isolating immunized animal lymphocytes; and (c) fusing the lymphocytes under appropriate fusion conditions with an immortalizing cell line to thereby obtain the hybridoma.

REFERENCES:
patent: 4272504 (1981-06-01), Kim et al.
patent: 4349528 (1982-09-01), Koprowski
G. Kohler et al., Nature, 256 (5517), 495-497 (Aug. 7, 1975).
M. Votila et al., J. Immunol. Methods, 42(1), 11-15 (1981).
Shevinsky, L. et al., CELL, 30:697 (1982).
Sato, M. et al., Development, Growth and Differentiation, 25:333 (1983).
Coggin, Jr., J. H. et al., in Fetal Antigens and Cancer, Pittman, London (CIBA Foundation Symposium 96), p. 28 (1983).
Evans, D. et al., Cancer Research, 39:2006 (1979).
Coggin, Jr., J. H. et al., Journal of Immunology, 107:526 (1971).
Hanna, Jr., M. G. et al., Proc. Nat. Acad. Sci. USA, 68:1748 (1971).
Ting, C. C. et al., In Vitro, 14:207 (1978).
Weppner, W. A. et al., Cancer Research, 40:1380 (1980).
Coggin, Jr., J. H., Cancer Research, 39:2952 (1979).
Coggin, Jr., J. H. et al., Journal of Immunology, 105:524 (1970).
Gupta, R. K. et al., Journal of the National Cancer Institute, 70:993 (1983).
Kennett, R. H. et al., Science, 203:1120 (1979).
Pasternak, G. et al., Journal of the National Cancer Institute, 69:997 (1982).

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