Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2006-10-10
2006-10-10
Ceperley, Mary E. (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S006120, C435S007100, C435S183000, C436S501000, C436S527000, C436S528000, C436S532000, C536S023100, C536S024300
Reexamination Certificate
active
07118908
ABSTRACT:
An on-spot selectively activated hydrophobic slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing a functional group protected by a protecting group, wherein the functional group is imide or cyclic amide, and the protecting group is a photo acid group such as a tosyloxy group. The hydrophobic copolymer coated on a substrate is then subjected to selective photolithographical activation so that the slide will have functional active copolymer spots separated by inactive copolymers. The resulting slide is suitable for the preparation of high-density and high-efficiency bio-chip/microarray.
REFERENCES:
patent: 5272042 (1993-12-01), Allen et al.
patent: 5445934 (1995-08-01), Fodor et al.
Ho Chih-Wei
Jan Bor-Iuan
Pan Chao-Chi
Tsao Jia-Huey
Bingham & McCutchen LLP
Ceperley Mary E.
Chao Fei-Fei
Haq Shafiqul
Jan Bor-Iuan
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