On-column junction for capillary columns

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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204299R, 73 6158, 73 6153, G01N 2726, G01N 27447

Patent

active

053104633

ABSTRACT:
An electrophoretic or chromatographic separation capillary containing a fluid defines a bore therein through which a sample travels and separates into components. The tube has a side wall defining a through hole therein which is surrounded by a medium including a substance. The substance is introduced into the capillary through the hole by means of gravity, pressure or electroosmosis. The substance introduced may be used to label sample components to enhance detection, or to enhance separation of sample components.

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Stephen L. Pentoney, Jr. et al "On-line Connector for Microcolumns: Application to the On-Column o-Phthaldialdehyde Derivatization of Amino Acids Separated by Capillary Zone Electrophoresis" Analytical Chemistry vol. 60, No. 23(1988) 2625-2629.
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"On-Column Connector for Microcolumns: Application to the o-Phthaldialdehyde Derivatization of Amino Acids . . . ," by Pentoney, Jr., et al., American Chem. Soc., 60(23):2625-2629 (Dec. 1, 1988).
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Article entitled "Capillary-Zone Electrophoresis with Fraction Collection . . . ," by Takigiku et al., CZE for Desorption MS.

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