On-chip phase microscope/beam profiler based on differential...

Optics: measuring and testing – By light interference – Having wavefront division

Reexamination Certificate

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Reexamination Certificate

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07982883

ABSTRACT:
A differential interference contrast (DIC) determination device and method utilizes an illumination source, a layer having a pair of two apertures that receive illumination from the illumination source, and a photodetector to receive Young's interference from the illumination passing through the pair of two apertures. In addition, a surface wave assisted optofluidic microscope and method utilize an illumination source, a fluid channel having a layer with at least one aperture as a surface, and a photodetector that receives a signal based on the illumination passing through the aperture. The layer is corrugated (e.g., via fabrication) and parameters of the corrugation optimize the signal received on the photodetector.

REFERENCES:
patent: 5196350 (1993-03-01), Backman et al.
patent: 5426505 (1995-06-01), Geiser et al.
patent: 6858436 (2005-02-01), Zenhausern et al.
patent: 2007/0172745 (2007-07-01), Smith
patent: 2007/0207061 (2007-09-01), Yang et al.
Arnison, M.R., et al., “Linear phase imaging using differential interference contrast microscopy,” Journal of Microscopy, vol. 214, Pt. 1, pp. 7-12 (Apr. 2004).
Bouwkamp, C.J., “Diffraction theory,” Reports on Progress in Physics XVII, pp. 35-100 (1954).
Cui, Xiquan, et al., “Portable optical microscope-on-a-chip,” Photonics West, San Jose, CA (Jan. 2006).
Cui, Xiquan, et al., “Slanted hole array beam profiler (SHArP)-a high-resolution portable beam profiler based on a linear aperture array,” Optics Letters, vol. 31, No. 21, pp. 3161-3163 (Nov. 2006).
Doyle, Patrick S., et al., “Self-assembled magnetic matrices for DNA separation chips,” Science, vol. 295, No. 5563, p. 2237 (Mar. 2002).
Dunn, et al., “Introduction to Confocal Microscopy,” available from MicroscopyU at http://www.microscopyu.com/articles/confocal (2007).
Ebbesen, T.W., et al., “Extraordinary optical transmission through sub-wavelength hole arrays,” Nature, vol. 391 (6668), pp. 667-669 (Feb. 1998).
Fu, Anne Y., et al., “A microfabricated fluorescence-activated cell sorter,” Nature Biotechnology, vol. 17, pp. 1109-1111 (Nov. 1999).
Garcia De Abajo, F.J., “Light transmission through a single cylindrical hole in a metallic film. Optics Express,” vol. 10, No. 25, pp. 1475-1484 (2002).
Heng, Xin, et al., “Optofluidic Microscope, a miniature microscope on a chip,” 9th International Converence on Miniaturized Systems for Chemistry and Life Sciences (μTAS) (2005).
Lezec, H.J., et al., “Beaming Light from a Subwavelength Aperture,” Science, vol. 297, No. 5582, pp. 820-822 (2002).
Lezec, H.J., and Thio, T., “Diffracted evanescent wave model for enhanced and suppressed optical transmission through subwavelength hole arrays,” Optics Express, vol. 12, No. 16, pp. 3629-3651 (Aug. 2004).
Liu, Shaorong. “A microfabricated hybrid device for DNA sequencing,” Electrophoresis 2003, vol. 24(21), pp. 3755-3761 (2003).
Murphy, et al., “Differential Interference Contrast (DIC),” available from Nikon MicrocopyU at http://www. microscopyu.com/articles/dic/dicindex.html (2007).
Tegenfeldt, Jonas 0., et al., “Micro-and nanofluidics for DNA analysis,” Analytical and Bioanalytical Chemistry, 378(7), pp. 1678-1692 (2004).
Tegenfeldt, Jonas 0., et al., “Near-field Scanner for Moving Molecules,” Physical review letters, 86(7), vol. 86, No. 7, pp. 1378-1381 (Feb. 2001).
Tokeshi, Manabu, et al., “Chemical processing on microchips for analysis, synthesis, and bioassay,” Electrophoresis, vol. 24, No. 21, pp. 3583-3594 (2003).
Trau, D., et al., “Genotyping on a complementary metal oxide semiconductor silicon polymerase chain reaction chip with integrated DNA microarray,” Analytical Chemistry, vol. 74, No. 13, pp. 3168-3173 (2002).

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