On chip dilution system

Details On chip dilution system On chip dilution system

2008-07-22

2008-07-22

Sorkin, David L (Department: 1797)

Agitating

Having specified feed means

Responsive to condition sensor

C366S160100, C366S182400, C073S001360

Reexamination Certificate

active

07401972

ABSTRACT:
An on-chip chemical compound dilution system for providing dilution of a chemical compound in a microfluidic application includes at least one sample well for providing a selected chemical compound to be diluted, a dilution well for providing a diluent for diluting the chemical compound, a network of channels for carrying the chemical compound and diluent, a first syringe pump for effecting dilution, a second syringe pump, a detector and a plurality of valves for selectively controlling the flow of liquid through the channels. The dilution system may be a multiple-stage dilution system for precisely mixing a plurality of chemical compounds in a diluent. The dilution system allows for accurate calibration to compensate for variations due to manufacturing, thereby providing precise dilution ratios. The dilution system further enables flushing to allow re-use of the system with another chemical compound.

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