Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-11-29
2010-02-16
Devi, S. (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069100, C435S071100, C435S069700, C424S184100, C424S234100, C424S190100, C424S192100
Reexamination Certificate
active
07662588
ABSTRACT:
Nucleic acid and amino acid sequences of the Omp85 proteins ofN. gonorrhoeaeandN. meningitidis, and fragments thereof are useful in vaccine compositions, therapeutic compositions and diagnostic compositions for use in the prevention, treatment and diagnosis of non-symptomatic gonococcal infection or symptomatic disease and non-symptomatic meningococcal infection and symptomatic disease. Antibodies are developed to these proteins and also useful in the compositions and methods described herein.
REFERENCES:
patent: 5554372 (1996-09-01), Hunter
patent: 5698438 (1997-12-01), Stojiljkovic
patent: 5708155 (1998-01-01), Potter
patent: 5834591 (1998-11-01), Normark
patent: 5912336 (1999-06-01), Sparling
patent: 6197301 (2001-03-01), Flavell
patent: 6348185 (2002-02-01), Piwnica-Worms
patent: 6551795 (2003-04-01), Rubenfield et al.
patent: 6610306 (2003-08-01), Judd
patent: 6709660 (2004-03-01), Scarlato
patent: 2004/0033234 (2004-02-01), Berinstein et al.
patent: 2004/0126391 (2004-07-01), Scarlato
patent: 2005/0074458 (2005-04-01), Judd
patent: 2005/0191316 (2005-09-01), Fraser
patent: 2005/0287165 (2005-12-01), Scarlato
patent: 474313 (1992-03-01), None
patent: 1 535 928 (2008-07-01), None
patent: WO-92/03467 (1992-03-01), None
patent: WO-94/12641 (1994-06-01), None
patent: WO-98/21333 (1998-05-01), None
patent: WO-99/24578 (1999-05-01), None
patent: WO-99/36544 (1999-07-01), None
patent: WO-99/57280 (1999-11-01), None
Colman PM. Research Immunol. 145: 33-36, 1994.
Cruse et al., Illustrated Dictionary of Immunology, 2nd Edn., CRC Press, pp. 46, 166 and 382, 2003.
McGuinness et al. Mol. Microbiol. 7: 505-514, Feb. 1993.
McGuinness et al. Lancet 337: 514-517, Mar. 1991.
Bhasin et al. Infect. Immun. 69: 5031-5036, Aug. 2001.
Flack et al., “The Sequencing of the 80-kDA D15 Protective Surface Antigen ofHaemophilus influenzae”, Gene, 156-97-99 (Apr. 4, 1995).
Thomas et al., “Expression inEscherichia coliof a High-Molecular-Weight Protective Surface Antigen Found in Nontypeable and Type BHaemophilus influenzae”, Infection and Immunity, 58(6):1909-1913 (Jun. 1990).
Ruffolo et al., “Cloning, Sequencing, Expression, and Protective Capacity of the oma87 Gene Encoding thePasteurella multocida87-Kilodalton Outer Membrane Antigen”, Infection and Immunity, 64(8):3161-3167 (Aug. 1996).
Loosmore et al., “Outer Membrane Protein D15 is Conserved AmongHaemophilus influenzaeSpecies and May Represent a Universal Protective Antigen Against Invasive Disease”, Infection and Immunity, 65(9):3701-3707 (Sep. 1997).
Elkins et al., “Species-Specific Uptake of DNA byGonococciis Mediated by a 10-Base-Pair Sequence”, J. Bacteriology, 173(12):3911-3913 (Jun. 1991).
Von Heijne et al., “A New Method for Predicting Signal Sequence Cleavage Sites”, Nucleic Acids Research, 14 (11):4683-4690 (Jun. 11, 1986).
Struyve et al., “Carboxy-Terminal Phenylalanine is Essential for the Correct Assembly of a Bacterial Outer Membrane Protein”, J. Mol. Biol., 2118:141-148 (Mar. 5, 1991).
Altschul et al., “Basic Local Alignment Search Tool”, J. Mol. Biol., 215:403-410 (Oct. 5, 1990).
Tomb et al., “The Complete Genome Sequence of the Gastric PathogenHelicobacter pylori”, Nature, 388:539-547 (Aug. 1997).
Fraser et al., “Genomic Sequence of a Lyme Disease Spirochete,Borrelia burgdorferi”, Nature, 390:580-586 (Dec. 1997).
Koski et al., “Isolation, Cloning, and Primary Structure of a Cationic 16-kDa Outer Membrane Protein ofSalmonella typhimurium”, J. Biol. Chem., 264(32):18973-18980 (Nov. 1989).
Fleischmann et al., “Whole-Genome Random Sequencing and Assembly ofHaemophilus influenzaeRd”, Science, 269:496-512 (Jul. 1995).
Rossau et al., “Ribosomal Ribonucleic Acid Cistron Similarities and Deoxyribonucleic Acid Homologies ofNeisseria, Kingella, Eikenella, Simonsiella, Alysiella, and Centers for Disease Control Groups EF-4 and M-5 in the Amended Family Neiseriaceae”, International Journal of Systematic Bacteriology, 39:185-198 (Apr. 1989).
Schnell et al., “Isolation of Components of the Chloroplast Protein Import Machinery”, Science, 266:1007-1011 (Nov. 1994).
Kessler et al., “Identification of Two GTP-Binding Proteins in the Chloroplast Protein Import Machinery”, Science, 266:1035-1039 (Nov. 1994).
Newhall et al., “Cross-Linking Analysis of the Outer Membrane Proteins ofNeisseria gonorrhoeae”, Infection and Immunity, 28(3):785-791 (Jun. 1980).
Swanson et al., “Studies onGonococcusInfection, XII. Colony Color and Opacity Variants ofGonococci”, Infection and Immunity, 19(1):320-331 (Jan. 1978).
Laemmli et al., “Cleavage of Structural Proteins During the Assembly of the Head of Bacteriophage T4”, Nature, 227:680-685 (Aug. 1970).
Judd et al., “Purification of Outer Membrane Proteins of the Gram-Negative BacteriumNeisseria gonorrhoeae”, Analytical Biochemistry, 173:307-316 (Sep. 1988).
Moore, “Preparation and Analysis of DNA”, inCurrent Protocols in Molecular Biology, F.M. Ausubel et al., (eds), New York, John Wiley and Sons, Supplement 25, 2.1.1-2.1.3 (1995).
Southern, “Detection of Specific Sequences Among DNA Fragments Separated by Gel Electrophoresis”, J. Mol. Biol., 98:503-517 (Nov. 5, 1975).
Marchion et al., “Generation of Antiserum to Specific Epitopes”, Molecular Biotechnology, 6:231-240 (Dec. 1996).
Manning et al., “0mp85 Proteins ofNeisseria gonorrhoeaeandNeisseria meningitidisare Similar toHaemophilus influenzaeD-15-Ag andPasteurella multocidaOma87”, Microbial Pathogenesis, 25:11-21 (Jul. 1998).
Reschke et al., “Characterization of an 96 kDa Outer Membrane Protein ofNeisseria gonorrhoeaeHaving Homology with the D15 Surface Protective Antigen ofHaemophilus influenzae”, inPathogenic Neisseria, W. Zollinger et al. (eds), p. 44, NIH, Bethesda, MD (1996).
Cohen et al., “Mucosal Infection withNeisseria gonorrhoeae, Bacterial Adaptation and Mucosal Defenses”, J. Clin. Invest., 89:1699-1705 (Jun. 1992).
Kaneko et al., “Sequence Analysis of the Genome of the UnicellularCyanobacterium synechocystissp. Strain PCC 6803. II. Sequence Determination of the Entire Genome and Assignment of Potential Protein-Coding Regions”, DNA Research, 3:109-136 (Jun. 30, 1996).
Manning et al., “Neisseria gonorrhoeaeOuter Membrane Protein (omp85) Gene, Complete cds”, EMPRO Database Accession No. U81959 (Feb. 22, 1997).
Manning et al., “Neisseria meningitidisOuter Membrane Protein (omp85) Gene, Complete cds” EMPRO Database Accession No. AF021245 (Oct. 3, 1997).
Uhlen et al., “Gene Fusion Vectors Based on the Gene forStaphylococcalProtein A”, Gene, 23(3):369-378 (Sep. 1983) (Abstract).
Houghton et al., “Relative Importance of Position and Individual Amino Acid Residues in Peptide Antigen-Antibody Interactions: Implications in the Mechanism of Antigenic Drift and Antigenic Shift”, inVaccines, pp. 21-25, F. Brown et al., (eds), Cold Spring Harbor Laboratory (1986).
Lewis et al., “Identification of an Iron-Regulated Outer Membrane Protein ofNeisseria meningitidisInvolved in the Utilization of Hemoglobin Complexed to Haptoglobin”, J. Bacteriology, 177(5):1299-1306 (Mar. 1995).
Lewis et al., “Molecular Characterization of hpuAB, the Haemoglobin-Haptoglobin-Utilization Operon ofNeisseria meningitidis”, Molecular Microbiology, 23(4):737-749 (Feb. 1997).
Blasius et al., “Two Distinct Outer Membrane Serotype Subcomplexes ofNeisseria meningitidisSerogroup A”, Infection and Immunity, 58(6):2008-2010 (Jun. 1990).
Ferreiros et al., “Analysis of the Molecular Mass Heterogeneity of the Transferring Receptor ofNeisseria meningitidisand CommensalNeisseria”, FEMS Microbiology Letters, 83:247-254 (Oct. 15, 1991).
Dyer et al., “Isolation by Streptonigrin Enrichment and Characterization of a Transferrin-Specific Ir
Judd Ralph C.
Manning D. Scott
Devi S.
Howson & Howson LLP
The University of Montana
LandOfFree
Omp85 proteins of Neisseria gonorrhoeae and Neisseria... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Omp85 proteins of Neisseria gonorrhoeae and Neisseria..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Omp85 proteins of Neisseria gonorrhoeae and Neisseria... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4210964