Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-02-27
1993-06-15
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514400, 514564, 514926, 514927, 514966, 514970, 424436, A61K 3144, A61K 31415, A61K 31195, A61F 902
Patent
active
052198707
ABSTRACT:
This invention relates to omeprazole compositions designed for administration in the rectum, wherein said compositions comprise omeprazole, an active ingredient, a mixture of polyethylene glycols having molecular weights 1,000, 1,540, 4,000 and/or 6,000 or a mixture of adeps solidus and sodium laurylsulfate and a soluble, basic amino acid selected from arginine, lysine or histidine.
REFERENCES:
patent: 4255431 (1981-03-01), Junggren et al.
patent: 4432966 (1984-02-01), Zeitoun
patent: 4816568 (1989-03-01), Hamilton, Jr. et al.
The Merck Index, 11th Ed., #7545. Polyethylene Glycol, 1989.
Rackur, et al., 2-(2-pyridylmethyl)sulfinyl) benzimidazoles; Acid Sensitive Suicide Inhibitors of the Proton Transport System in the Parietal Cell, Apr. 16, 1985, 128 Biomedical and Biophysical Research Communications, pp. 477-485.
Pilbrant and Cederberg, Development of an Oral Formulation of Omeprazole; Mar. 1984 International Symposium in Finland, pp. 113-120.
Goldberg Jerome D.
Jordan Kimberly
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