Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-12-15
1978-01-10
Randolph, John D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424251, 424263, 260251R, 2602948R, C07D21346, C07D21352
Patent
active
040678776
ABSTRACT:
Straight- and branched-chain alkanes and 1-hydroxyalkanes of 4 to 18 carbon atoms, substituted in the .omega.-position by hetero-cyclic groups having the formula: wherein X is a methine group or a nitrogen atom and Y is oxygen or sulfur are prepared by reacting a haloalkane or a haloalkanol with an alkali metal salt of a compound containing the desired heterocyclic group, such as a pyridone or a substituted pyrimidine. The compounds have been found to be useful in accelerating the dark adaptation, as determined in tests with mice.
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Mikhailov et al., Izv. Akad. Nauk SSSR, vol. 11, pp. 2588-2591 (1974).
Knunjanz, Ber Deut. Chem. vol. 68, pp. 397 to 399 (1935).
Shepherd, et al., J. Am. Chem. Soc. vol. 64, pp. 2532 to 2537 (1942).
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Sharp, J. Chem. Soc. 1939, pp. 1855 to 1857.
Rath, Annalen der Chemie, vol. 484, pp. 52-64 (1930).
Binz et al., Annalen der Chemie, vol. 489, pp. 107-118 (1931).
Decker et al., Chemical Abstracts, vol. 6, pp. 225 to 227.
Randolph John D.
Robugen GmbH
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