.omega.-Aryl-cis-13-PGE compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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Details

260410, 2604105, 260408, 260413, 562463, 562464, C07C17700

Patent

active

041616057

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 4011262 (1977-03-01), Hess et al.

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