Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-09-12
1978-10-10
Douglas, Winston A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
26050116, 26050118, 560 60, 562470, 562465, C09F 700, C11C 300
Patent
active
041196490
ABSTRACT:
This invention comprises certain analogs PGE or 11-deoxy-PGE compounds in which the carbonyl at C-9 is replaced by methylene. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
REFERENCES:
patent: 3931299 (1976-01-01), Strike
Armitage Robert A.
Douglas Winston A.
Niebling John F.
The Upjohn Company
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