.omega.-Aryl-13,14-didehydro-inter-oxa PGF compounds

Details .omega.-Aryl-13,14-didehydro-inter-oxa PGF compounds .omega.-Aryl-13,14-didehydro-inter-oxa PGF compounds

1978-04-28

1979-07-03

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 53, 562465, C07C17700

Patent

active

041601050

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Abstract 18176Y/11 BE846-080, 10-03-77.
Derwent Abstract 79219X/42 U.S. 3984-400, 5-10-76.

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