.omega.-Aryl-13,14-didehydro-inter-oxa-PGA compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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562463, C07C17700

Patent

active

041397126

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 4005115 (1977-01-01), Bundy
patent: 4011249 (1977-03-01), Morozowich
patent: 4024179 (1977-05-01), Bindra et al.

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