Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-pheno

Details Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-pheno Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-pheno

1979-10-31

1981-06-09

Breitenstein, G. T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

2603437, 260465E, 260465F, 260465G, 2605011, 26050117, 26050119, 424330, 560 49, 564162, 564164, 564165, 564175, 564341, 564353, 564354, 564134, A61K 31135, A61K 31165, C07C 9306, C07C10326

Patent

active

042725500

ABSTRACT:
Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto having antihypertensive activity are preparable by reaction of the appropriate 2,3,6-substituted-4-(polyfluoro-2-hydroxy-2-propyl)phenol or thiophenol with an alkyl ester of a bromoalkanoic acid, followed by hydrolysis to the free acid.

REFERENCES:
patent: 3927092 (1975-12-01), Bolhofer
patent: 4117166 (1978-09-01), Baker et al.
patent: 4119433 (1978-10-01), Baker et al.
patent: 4148923 (1979-04-01), Giudicelli et al.
patent: 4199597 (1980-04-01), Neustadt et al.

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