Oligosaccharides having anti-Xa activity and pharmaceutical comp

Details Oligosaccharides having anti-Xa activity and pharmaceutical comp Oligosaccharides having anti-Xa activity and pharmaceutical comp

1980-10-06

1983-08-30

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated to proteinaceous toxin or fragment thereof

424180, 536 175, 536 21, A61K 31725, C08B 3710

Patent

active

044016620

ABSTRACT:
Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at least 30. They consist of chains constituted by no more than 8 saccharidic moities. They possess a strong antithrombotic activity and are then useful as antithrombotic drugs.

REFERENCES:
patent: 3506642 (1970-04-01), Koh et al.
patent: 3985871 (1976-10-01), Butti et al.
patent: 4122250 (1978-10-01), Schmer
patent: 4175182 (1979-11-01), Schmer
patent: 4213962 (1980-07-01), Miura et al.
patent: 4281108 (1981-07-01), Fussi

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