Oligosaccharide conjugate vaccines

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...

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530395, 530402, 530403, 530404, 530406, 530408, 530409, 530410, 530411, 530807, 424 88, 424 89, 424 92, C07K 1514, C07K 1702, A61K 39385

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051533120

ABSTRACT:
The present invention relates to an improved method for producing oligosaccharide conjugate vaccines. In an additional aspect of the invention, oligosaccharide vaccines are produced which elicit a monospecific and homogeneous immune response to capsular polysaccharide. A specific embodiment of the invention provides for vaccines which induce immunity to prevalent serotypes of Streptococcus pneumoniae.

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