Oligopeptide tyrosinase inhibitors and uses thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

Reexamination Certificate

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C530S327000, C530S328000

Reexamination Certificate

active

07902329

ABSTRACT:
Disclosed are peptides that inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. Peptide sequences disclosed include KFEKKFEK and YRSRKYSSWY.

REFERENCES:
patent: 3755560 (1973-08-01), Dickert et al.
patent: 3978427 (1976-08-01), Truscott
patent: 4421769 (1983-12-01), Dixon et al.
patent: 4522752 (1985-06-01), Sisto et al.
patent: 4554101 (1985-11-01), Hopp
patent: 5126327 (1992-06-01), Takeuchi et al.
patent: 5455228 (1995-10-01), Coller et al.
patent: 5543389 (1996-08-01), Yatvin et al.
patent: 5589460 (1996-12-01), Abajian et al.
patent: 5773291 (1998-06-01), Bouchard et al.
patent: 5789382 (1998-08-01), Wellstein
patent: 5854204 (1998-12-01), Findeis et al.
patent: 5962417 (1999-10-01), Gilchrest
patent: 6143723 (2000-11-01), Ramaiah
patent: 6165982 (2000-12-01), Yamada et al.
patent: 6256533 (2001-07-01), Yuzhakov et al.
patent: 6283978 (2001-09-01), Cheski et al.
patent: 6287590 (2001-09-01), Dasseux
patent: 6323219 (2001-11-01), Costanzo et al.
patent: 6602856 (2003-08-01), Quillan et al.
patent: 6663659 (2003-12-01), McDaniel
patent: 6695853 (2004-02-01), Karasiuk
patent: 6858581 (2005-02-01), Kuhner et al.
patent: 6982249 (2006-01-01), Schmaier et al.
patent: 7025957 (2006-04-01), Arquette
patent: 7083781 (2006-08-01), Fotinos
patent: 7125572 (2006-10-01), Lee
patent: 2002/0192738 (2002-12-01), Brissette et al.
patent: 2004/0086560 (2004-05-01), Chaudhuri et al.
patent: 2004/0175767 (2004-09-01), Orlow et al.
patent: 2006/0188462 (2006-08-01), Bissett et al.
patent: 2007/0088371 (2007-04-01), Karasiuk
patent: 9858967 (1998-12-01), None
patent: 2007001868 (2007-01-01), None
Hruby. Designing peptide receptor agonists and antagonists. Nature Reviews. Drug Discovery. Nov. 2002, vol. 1, pp. 847-858.
Giebel, Lutz B., et al., “Tyrosinase Gene Mutations Associated with Type IB (“Yellow”) Oculocutaneous Albinism,” Am. J. Hum. Genet., 1991, 48:1159-1167.
Scott, Charles P., et al., “Production of cyclic peptides and proteins in vivo,” Proc. Natl. Acad. Sci, Nov. 23, 1999, vol. 96, No. 24, 13638-13643.
Ohguchi, Kenji, et al., “Gnetol as a Potent Tyrosinase Inhibitor from GenusGnetum,” Biosci. Biotechnolo. Biochem., 2003, vol. 67, No. 3, 663-665.
Piao, Long Zhu, et al., “Mushroom Tyrosinase Inhibition Activity of Some Chromosomes,” Chem. Pharm. Bull., 2002, vol. 50, No. 3, 309-311.
Al-Obeidi, et al., “Synthesis and Biological Activities of Fatty Acid Conjugates of a Cyclic Lactam a-Melanotropin,” J. Med. Chem., 1992, vol. 35, 118-123.
Scimonelli, et al., “Inhibition by L-Protyl-L-Leucyl-Glycinamide (PLG) of Alpha-melanocyte stimulating hormone release from hypothalamic slices,” Peptides, Nov. 1992, vol. 3, No. 6, 885-889. (Abstract).
Fletcher, et al., “Partially Modified Retro-Inverso Peptides: Development, Synthesis, and Conformational Behavior,” Chemical Reviews, Mar. 1998, vol. 98, 763-795.
PCT/3815.41A-1 International Search Report, mailed Oct. 22, 2008.
PCT/3815.41A-1 Written Opinion of the International Searching Authority, mailed Oct. 22, 2008.
PCT/3815.41B-1 International Search Report, mailed Nov. 14, 2008.
PCT/3815.41B-1 Written Opinion of the International Searching Authority, mailed Nov. 14, 2008.

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