Oligonucleotides with anti-Epstein-Barr virus activity

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits

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4352402, 536 231, 536 2372, 536 245, 514 44, 935 8, 935 34, C12N 500, C12N 706, A61K 4800, C07H 2104

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active

055500471

ABSTRACT:
Disclosed are oligonucleotides complementary to and hybridizable with a portion of the BZLF1 RNA of Epstein-Barr virus, useful for inhibiting the induction of the lytic cycle in EBV-infected cells, and in inhibiting EBV replication.

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