Oligonucleotides with anti-Epstein-Barr virus activity

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435238, 435375, 514 44, C07H 2100, A61K 3170, C12N 510

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active

058378545

ABSTRACT:
Oligonucleotides that inhibit Epstein-Barr virus functions, pharmaceutical compositions containing such oligonucleotides, and methods of using these compositions to treat Epstein-Barr virus-associated diseases.

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Roth et al., "Epstein-Barr Viral Nuclear Antigen 1 Antisense Oligodeoxynucleotide Inhibits Proliferation of Epstein-Barr Virus-Immortalized B Cells", Blood 84:582-587, 1994.
Tsubota et al., "Inhibited LMP Expression of EBV-Immortalized Lymphoblastoid Cells By Antisense Oligonucleotides", Investigative Ophthalmology & Visual Science 36:s992, Abstract 4592-573, 1995.

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