Oligonucleotides with anti-cytomegalovirus activity

Details Oligonucleotides with anti-cytomegalovirus activity Oligonucleotides with anti-cytomegalovirus activity

1994-05-25

1998-09-01

Degen, Nancy

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435375, 536 243, 536 2433, C07H 2102, C07H 2104, C12Q 168, C12N 516

Patent

active

058012354

ABSTRACT:
Disclosed are synthetic oligonucleotides 15 to 50 nucleotides in length which are specifically hybridizable with at least a portion of RNA or DNA derived from the UL36, UL84, UL101x-102, or UL112-113 genes of a cytomegalovirus. Also disclosed are pharmaceutical compositions including an oligonucleotide of the invention and methods of inhibiting cytomegalovirus infection using such oligonucleotides.

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