Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2011-02-08
2011-02-08
Angell, J. E (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
Reexamination Certificate
active
07884084
ABSTRACT:
The present application relates to antisense oligonucleotides which inhibit expression of the OB-RGRP protein and to uses thereof for preventing and/or treating leptin-related pathological conditions.It also relates to a method for detecting compounds which modify the interaction between proteins of the OB-RGRP family and the leptin receptor. This detection may be carried out by measuring the energy transfer between fusion proteins composed of these proteins and of energy-donor and -acceptor proteins.
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Couturier Cyril
Jockers Ralf
Uhlmann Eugen
Angell J. E
Aventis Pharma S.A.
Centre National de la Rechercher Scientifique
Institut National de la Sante et de la Recherche Medicale
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