Oligonucleotides specific for the MOMP gene sequence and methods

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 6, 536 2433, 536 2432, 935 77, 935 78, C12P 1934, C12Q 168, C07H 2104

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058467858

ABSTRACT:
The present invention relates to oligonucleotide probes useful in detecting, e.g. by hybridization or the ligase chain reaction, Chlamydia trachomatis DNA in the presence of other related DNA. The present invention is also directed to methods of detecting Chlamydia trachomatis organisms in a sample using the ligase chain reaction.

REFERENCES:
Dille et al. (1993) J. Clin. Microbiol. 31(3):729-731.
Pickett et al. FEMS Microbiol. Lett. 42 (1987) 185-190.
Stephens et al. (1987) J. Bact. 169(9):3879-3885.
Baehr et al. (1988) PNAS 85 : 4000-4004.
Sayada et al. Gene (1992) 120:129-130.
Zhang et al. NAR (1989) 18(4) : 1061.
He et al. Biotechniques 17(1) : 82,84,-86 (1994).

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