Oligonucleotides specific for hepatitis B virus

Details Oligonucleotides specific for hepatitis B virus Oligonucleotides specific for hepatitis B virus

1995-06-06

1999-01-05

Ketter, James

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 2100

Patent

active

058564594

ABSTRACT:
The present invention discloses synthetic oligonucleotides complementary to contiguous and noncontiguous regions of the HBV RNA. Also disclosed are methods and kits for inhibiting the replication and expression of HBV, and for treating HBV infections and associated conditions.

REFERENCES:
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Gura Antisense has growing pains Science vol. 270 575-577, 1995.
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Offensperger et al. (1993) EMBO J. 12:1257-1262.
Reinis et al. (1993) Folia Biologica (Praha) 39:262-269.
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