Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-05-02
2006-05-02
Wang, Andrew (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C436S173000
Reexamination Certificate
active
07038036
ABSTRACT:
Antisense oligonucleotide sequences which enable the measurement of the distribution and structure of antisense oligonucleotide drugs in the body, with lapse of time, and a method of detecting these sequences are provided. The antisense chains have a natural or non-natural nucleotide or peptide nucleic acid as a structural unit in which carbon atoms and nitrogen atoms are substituted by13C and15N, respectively, and the antisense chains can be detected by nuclear magnetic resonance spectroscopy (NMR) such as15N—1H or13C—1H hetero nuclear multiple quantum coherence spectroscopy.
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Kawai Gota
Takaku Hiroshi
Wada Akira
J.C. Patents
Taiyo Nippon Sanso Corporation
Vivlemore Tracy
Wang Andrew
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