Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1989-05-15
1991-06-11
Martinell, James
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 27, 435 91, 935 34, C07H 2104, A61K 31725, A61K 4800
Patent
active
050232436
ABSTRACT:
For use in controlling biologic functions in an organism, a stabilized oligonucleotide, preferably in a phosphotriester form, having a base sequence substantially complementary to a portion of messenger ribonucleic acid coding for a biological component, such as a protein, of the organism. The oligonucleotide has about fourteen bases or more, such as twenty-three bases, and can be a deoxyribonculeotide. The oligonucleotide sequence can be derived from the organism's ribonucleic or deoxyribonucleic acid that codes for a vital protein, and can be synthesized in bulk either chemically or by insertion into a plasmid.
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Martinell James
Molecular Biosystems, Inc.
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