Oligonucleotide probes for the determination of the proclivity f

Details Oligonucleotide probes for the determination of the proclivity f Oligonucleotide probes for the determination of the proclivity f

1988-06-10

1991-10-22

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 27, C12Q 168, C07H 1512

Patent

active

050595199

ABSTRACT:
DQ beta gene oligonucleotides consisting essentially of the sequence GGCCGCCTGCCGCCGAG or of the sequence GCTGGGGCTGCCTGCCG and the use of such oligonucleotides in a method for assaying for a polymorphic region associated with Type I diabetes mellitus in humans.

REFERENCES:
Spies et al., PNAS 82 5165-5169 (1985).
Boss et al. Proc. Natl. Acad. Sci. 81 5199-5203 (1984).
Gustafson et al. EMBOJ 3 1655-1661 (1984).
Maniatis et al. Molecular Cloning (1982) Cold Spring Harbor Press, Cold Spring.
Long et al. EMBOJ 2 (3) 389-394 (1983).
Angelini et al. Proc. Natl. Acad. Sci. 83 4489-4493 (1986).
Larhammor et al. Proc. Natl. Natl. Acad. Sci 82 1475-1479 (1985).
Larhammer et al. Proc. Natl. Acad. Sci. 80 7313-7317, 1983.
Owerbach et al., Immunogenetics 24: 41-46 (1986).

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