Oligonucleotide probes for detection of periodontal pathogens

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 42, 435170, 536 231, 536 243, 536 2432, 935 77, 935 78, 935 79, C12Q 168, C12P 3900, C12P 1934, C07H 1700

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053786041

ABSTRACT:
This invention relates to compositions of oligonucleotide probes for use in the detection of bacteria associated with medical disorders of the human mouth, wherein said probes consist essentially of a segment of nucleic acid capable of selectively hybridizing under hybridizing conditions, to the 16S or 23S ribosomal RNA [rRNA] of said bacteria. Methods for detection, as well as diagnostic kits for the assay of these bacterium, are also disclosed.

REFERENCES:
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Oral Microbiol. and Immunol. vol. 1, No. 1, Oct. 1986, Copenhagen DK, pp. 58-62 French, C. K. et al. `Dna probe detection of periodontal pathogens`.
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