Oligonucleotide phosphonates and method of inhibiting a human im

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 27, 536 28, 536 29, 435 6, A61K 3170

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051108020

ABSTRACT:
A method of inhibiting human immunodeficiency virus (HIV) comprising administering a therapeutically effective amount of an antiviral agent to attack the first splice acceptor site of the tat III gene of HIV.

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Mitsuya et al., "Protection of T Cells against Infectivity and Cytopathic Effect of HTLV-III In Vitro Retroviruses in Human Lymphoma/Leukemia", Miwa et al. eds., VNU Science Press, Utrecht, 1985, pp. 277-288.
Altmann, "AIDS Epidemic Puts an Unusual Microbe Under Scrutiny", The N.Y. Times, New York, Jun. 26, 1990, p. C3.
Zamecnik et al., Proc. Nat. Acad. Sci. USA, vol. 83, pp. 4143-4146, 1986.

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