Oligonucleotide for detection of HIV-1 and detection method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C424S208100, C435S005000, C435S091200, C435S091210, C536S024300

Reexamination Certificate

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07049067

ABSTRACT:
An oligonucleotide useful for detection of an RNA derived from HIV-1 consisting of at least 10 consecutive bases in any of SEQ ID NOS:1, 2, 4 to 10 and 13 to 17, which can bind to a specific site of the RNA.

REFERENCES:
README.txt file from CD-ROM of Professor Andrew Chin.
SHORT.txt file pp. 1-2 of CD-ROM of Professor Andrew Chin.
http:/
ewport.lib.unc.edu/web2/tramp2.exe/authority—hits/A2oicjn4.001?server=3home&item=1.
McDonough, S.H. et al., (1998) “High Throughput Analysis for the Simultaneous or Separate Detection of Human Immunodeficiency Virus (HIV) and Hepatitis Type C Virus (HCV)” Infusionstherapie und Trasnfusionmedizin 25: 164-169.
Muesing, M.A. et al. (1999) “Human Immunodeficiency Virus Type 1, isolate PV22, complete Genome (H9 / HTLV III Proviral DNA)” NCBI PubMed Accession No. K02083.
Muesing, M.A. et al. (1985) “Human Immunodeficiency Virus Type 1, isolate PV22, complete Genome (H9 / HTLV III Proviral DNA)” Nature 313: 450-458.
Romano, J.W. et al. (1995) “Detection of HIV-1 Infection in vitro Using NASBA: an isothermal RNA amplification technioque,”J. Virol. Meth. 54:109-119.
Romano, J.W. et al. (1996) “NASBA A Novel, Isothermal Technology for Qualitative and Quantitative HIV-1 RNA Measurements,”Clin. Lab. Meth. 16: 89-103.
Van Gemen, B. et al. (1995) “The One-Tube Quantitative HIV-1 RNA NASBA: Precision, Accuracy and Application,” PCR Methods and Applications 4:S177-S184.
Search Report of the European Patent Office, European Patent Application EP 01 12 5378.

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