Oligonucleotide-cyclopropapyrroloindole conjugates as sequence s

Details Oligonucleotide-cyclopropapyrroloindole conjugates as sequence s Oligonucleotide-cyclopropapyrroloindole conjugates as sequence s

1996-01-05

1997-08-19

Marschel, Ardin H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 243, C07H 1900, C07H 2102, C07H 2104, A01N 4304

Patent

active

056590229

ABSTRACT:
Covalently linked conjugates of oligonucleotides (ODNs) with a cyclopropapyrroloindole moiety or an analog thereof, selectively and efficiently alkylate and crosslink with nucleic acid sequences that are complementary to the base sequence of the ODN.

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