Oligonucleotide analogues containing phosphate diester linkage s

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 245, 514 44, 435 6, C07H 2104

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056774397

ABSTRACT:
The present invention relates to compounds, compositions and methods for inhibiting gene expression. The compounds of this invention comprise 1) oligonucleoside sequences of from about 6 to about 200 bases having a three atom internucleoside linkage or 2) oligonucleotide sequences of from about 9 to about 200 bases having a diol at either or both termini.

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