Oligomers substituted by phosphite acid ester, phosphonic...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S017100, C536S022100, C536S025600, C536S026100

Reexamination Certificate

active

07105648

ABSTRACT:
The invention relates to novel oligomers containing PNA units that are substituted by phosphite ester, phosphonic acid, or carbaborane functions and PNA monomers that are substituted by phosphite ester, phosphonic acid, or carbaborane functions, from which the novel oligomers are produced.

REFERENCES:
patent: 5846741 (1998-12-01), Griffiths et al.
patent: WO 98/42735 (1998-10-01), None
Egholm, Michael et al., “Peptide Nucleic Acids (PNA). Oligonucleotide Analogues with an Achiral Peptide Backbone,” Journal of the American Chemical Society, 1992, 114 (5), 1895-1897.
Kane, Robert R. et al., “Solution-Phase Segment Synthesis of Boron-Rich Peptides,” Journal of Organic Chemistry, 1993, 58 (5), 991-992.
Varadarajan, Aravamuthan et al., “Novel Carboranyl Amino Acids and Peptides: Reagents for Antibody Modification and Subsequent Neutron-Capture Studies,” 1991, 2 (4), 242-253.

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