Oligomers containing N-acetyl glucosamine (NAG)

Details Oligomers containing N-acetyl glucosamine (NAG) Oligomers containing N-acetyl glucosamine (NAG)

2005-12-20

2005-12-20

Seidleck, James J. (Department: 1711)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

C536S055200, C536S017200, C536S018700, C536S022100, C526S238200, C526S238220, C526S238230, C527S312000

Reexamination Certificate

active

06977285

ABSTRACT:
Functional polyvalent oligomer for applications in medicine and biotechnology are disclosed. These oligomers have the formula (1)wherein R is H, CH3, C2H5, R1, is H, NH2, OH, COOH, X is N-Acetyl Glucosamine, mannose, galactose and sialic acid, fructose, ribulose, erythrolose, xylulose, psicose, sorbose, tagatose, glucopyranose, fructofuranose, deoxyribose, galactosamine, sucrose, lactose, isomaltose, maltose, cellobiose, cellulose and amylose, Y is H, COOH, OH or NH2, and n is from 3 to 50. The present invention also relates to synthesis of such oligomeric ligands. The method of synthesis of the present invention for oligomerization can be—applied to other ligands such as sialic acid, mannose and galactose and can -be used for the prevention of infections.

REFERENCES:
patent: 4465827 (1984-08-01), Kawasaki et al.
patent: 6605714 (2003-08-01), Vaidya et al.
patent: 2002/0098567 (2002-07-01), Vaidya et al.
patent: 1099372 (1968-01-01), None
patent: 94/14823 (1994-07-01), None
Vaidya, et al., Termoprecipitation of Lyosome from egg ahite using copolymers of N-isopropylacrylamide and acific monomers:, May, 2001, Journal of Bioutechnology, Isue 2, V. 87, pp. 95-107.

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