Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-08-30
2005-08-30
Goldberg, Jeanine A. (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S287200, C536S023100, C536S024300
Reexamination Certificate
active
06936419
ABSTRACT:
An oligomer array with PNA (peptide nucleic acid) and/or DNA oligomers on a surface is described, which comprises oligomers of between 6 and 20 monomers or nucleobases each, whereby each of these contains at least one sequence of the general formula DDCGDD or of the general formula DDTGDD or of the general formula HHCGHH or of the general formula HHCAHH, whereinH indicates one of the bases: adenine (A), cytosine (C), or thymine (T) andD represents one of the bases: adenine (A), guanine (G) or thymine (T),and wherein the site of the oligomers on the surface is correlated with the sequence of the oligomers.The oligomer arrays according to the invention are used for the detection of cytosine methylations in genomic DNA.
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Epigenomics AG
Goldberg Jeanine A.
Kriegsman & Kriegsman
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