Oligodeoxynucleotide and its use to induce an immune response

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C424S184100, C424S278100, C424S450000

Reexamination Certificate

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07960356

ABSTRACT:
D type CpG oligodeoxynucleotides are provided herein that include a sequence represented by the following formula:in-line-formulae description="In-line Formulae" end="lead"?5′ X1X2X3Pu1Py2CpG Pu3Py4X4X5X6(W)M(G)N-3′in-line-formulae description="In-line Formulae" end="tail"?wherein the central CpG motif is unmethylated, Pu is a purine nucleotide, Py is a pyrimidine nucleotide, X and W are any nucleotide, M is any integer from 0 to 10, and N is any integer from 4 to 10. Methods of using these oligodeoxynucleotides to induce an immune response are provided.

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