Oligo or polyalkylene glycol-coupled thrombin inhibitors

Details Oligo or polyalkylene glycol-coupled thrombin inhibitors Oligo or polyalkylene glycol-coupled thrombin inhibitors

2002-01-23

2008-08-05

Shameem, Golam M. M. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S408000

Reexamination Certificate

active

07407982

ABSTRACT:
The present invention relates to novel covalent oligo and polyalkylene glycol conjugates with synthetic inhibitors of trypsin-type serine proteases, in particular inhibitors of the hemocoagulation protease thrombin, synthetic intermediates stages required in their production and their use for producing active ingredients for the treatment or prophylaxis of thrombotic complications.

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