Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
2001-12-19
2004-05-25
Coleman, Brenda (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
active
06740753
ABSTRACT:
SUMMARY
This invention relates to a novel crystal form of the pharmaceutical compound olanzapine, a process for its preparation and pharmaceutical formulations thereof.
BACKGROUND
The compound 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno{2,3-b}{1,5}benzodiazepine been named according to the U.S.A.N. as olanzapine. It is known as an anti-psychotic agent. The present invention relates to a novel olanzapine crystal modification, hereinafter designated as Form X, which is distinguished from previously known crystal forms by physical and spectroscopic properties such as melting point and powder x-ray diffraction pattern.
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Davies Julian
Gano James Edward
Coleman Brenda
Furman Diane E.
Geneva Pharmaceuticals Inc.
Lopez Gabriel
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