Oily phase in an aqueous phase dispersion stabilized by cubic ge

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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424405, 424 701, 424 761, 424 61, 424450, 514939, 252312, A61K 700, A01N 2504

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active

057561087

ABSTRACT:
Composition in the form of a stable dispersion. This composition comprises:
(a) from 60 to 98% by weight of an aqueous phase, and (b) from 2 to 40% by weight of an oily phase, said oily phase being dispersed in said aqueous phase and stabilized using cubic gel particles, said particles being essentially formed of:
(i) 0.1 to 15% by weight, relative to the total weight of the composition, of at least one component selected from the group consisting of 3,7,11,15-tetramethyl-1,2,3-hexadecanetriol or phytanetriol, N-2-alkoxycarbonyl derivatives of N-methylglucamine and unsaturated fatty acid monoglycerides, and
(ii) 0.05 to 3% by weight, relative to the total weight of the composition, of a dispersing and stabilizing agent, said agent being selected from the group consisting of surface-active agents which are water-soluble at room temperature, containing a linear or branched, saturated or unsaturated fatty chain having from 8 to 22 carbon atoms. Use in particular in the cosmetic, dermatological and pharmaceutical fields.

REFERENCES:
patent: 5151272 (1992-09-01), Engstrom et al.
patent: 5443840 (1995-08-01), Morancais et al.
patent: 5531925 (1996-07-01), Landh et al.
patent: 5569663 (1996-10-01), Ribier et al.
patent: 5593663 (1997-01-01), Leng et al.
Simon Benita, Microencapsulation: Methods and Industrial Applications (Marcel Dekker, Inc., NY, NY, copyright 1996) pp. 415-417, 1996.
Sven Engstrom, "Drug Delivery From Cubic and Other Lipid-Water Phases"; Lipid Technology, vol. 2, No. 2, Apr. 1990, pp. 42-45.

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