Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1994-06-13
1997-09-09
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424455, 424456, 424452, A61K 3537, A61K 3538
Patent
active
056653840
ABSTRACT:
Stable, pharmaceutical ketoprofen salts for oral administration are provided in oily solutions to avoid direct contact of acid forms of ketoprofen with the gastric or duodenal mucus membranes. Sodium, arginine, lysine and/or N-methylglucamine salts of ketoprofen are disclosed in solutions of polyoxyethyenatide vegetable oil, castor oil, esters of fatty acids and/or polyols. These oily solutions of ketoprofen may be administered orally in capsule form.
REFERENCES:
patent: 4627850 (1986-12-01), Deters et al.
patent: 4944949 (1990-07-01), Story et al.
Courteille Frederic
Veillard Michel
Benston, Jr. William E.
Oehler Ross J.
Page Thurman K.
Rhone-Poulenc Rorer S.A.
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