Off-resonance spin-locking for enhanced tumor contrast in NMR im

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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324307, G01V 300

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052819175

ABSTRACT:
Contrast between tumor and normal fat and normal fibro-glandular breast tissues is enhanced in an NMR image by a preparatory pulse sequence executed prior to the imaging pulse sequence. An off-resonance spin-locking RF pulse is employed to enhance contrast between fibro-glandular tissue and tumors and an inversion recovery sequence is employed to enhance contrast between fat and tumors.

REFERENCES:
patent: 4876508 (1989-10-01), Taylor
patent: 5001427 (1991-03-01), Fujiwara
Off Resonance field pulsing for Contrast Manipulation in MRI: Application to Human Breast Tissues, G. E. Santyr, et al., SMRM 1988, p. 1046.
Spin Locking for Magnetic Resonance Imaging with Application to Human Breast, G. E. Santyr et al., Magnetic Resonance in Medicine 12, 25-37 (1989).

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