Ocular therapy with homologous macrophages

Details Ocular therapy with homologous macrophages Ocular therapy with homologous macrophages

1993-10-06

1997-10-14

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

424 937, A61K 3514

Patent

active

056769440

ABSTRACT:
The treatment of glaucoma and other conditions relating to diseased trabecular meshwork in the eye is effected by administration of macrophages and/or cytokines to the eye. Increased levels of macrophages within the anterior chamber of the eye will at least partially clear obstruction of the trabecular meshwork and restore viability of trabecular cells in order to enhance release of aqueous fluid from the anterior chamber and reduce intraocular pressures. The administration of cytolines will either recruit macrophages or will effect repair of the trabecular meshwork cells directly.

REFERENCES:
patent: 4878895 (1989-11-01), Klesius et al.
patent: 5260059 (1993-11-01), Acott et al.
patent: 5324508 (1994-06-01), Adelstein et al.
Tripathi et al., Invest Opthalmol. Vis Sci 34(8): 2562-2568 (Jul. 1993).
Wakefield et al., Cytokine (Philadelphia) 4(1): 1-5 (1992).
Gillies, Aust N. Z. J. Opthalmol. 19(4): 299-304 (Nov. 1991).
Feder et al. (1984) Int. Opthal. 7:87-93.
Epstein et al. (1986) Invest. Ophthalmol. Vis. Sci. 27:387-395.
Kampik et al. (1981) Am. J. Ophthalmol. 91:573-587.
Shiuey et al. (1992) Abstract 2332-7 Invest. Ophthalmol. Vis.
Alvarado et al. (1986) Arch. Ophthal. 104:1517-1528.
Murphy et al. (1992) Arch. Ophthal. 110:1769-1778.
Acott et al. (1989) Am. J. Ophthalmol. 107:1-6.
Dueker et al. (1990) Invest. Ophthalmol. Vis. Sci. 31:115-124.
Alvarado et al. (1992) Arch. Ophthalmol. 110:1779-1785.
Shiuey et al. (1993) Abstract 3365-11 Invest. Ophthal. Vis.
Alvarado et al. (1984) Ophthal. 91:564-579.

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