Ocular therapy in keratoconjunctivitis sicca using topically app

Details Ocular therapy in keratoconjunctivitis sicca using topically app Ocular therapy in keratoconjunctivitis sicca using topically app

1999-03-17

2000-08-22

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514912, A61K 3156

Patent

active

061072893

ABSTRACT:
The topical application, at a dose rate less than or equal to 0.1 mg day, to the ocular surface or adjacent regions of the eye of a preparation containing a therapeutically effective amount of an androgen or androgen analogue or a therapeutically effective amount of TGF-.beta. is disclosed as a method of relieving the chronic and acute manifestation of dry eye signs and symptoms in keratoconjunctivitis sicca (KCS), for example in Sjogren's syndrome.

REFERENCES:
patent: 4617299 (1986-10-01), Knepper
patent: 4642305 (1987-02-01), Johansson et al.

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