Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2008-01-22
2008-01-22
Chan, Christina (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S069100, C435S070100, C530S350000, C436S501000
Reexamination Certificate
active
07320870
ABSTRACT:
The present invention relates to a novel lacrimal gland protein (designated lacritin) and the nucleic acid sequences encoding that protein. Lacritin has activity as a growth factor on both human corneal epithelial cells and on the lacrimal acinar cells that produce it. Accordingly, one embodiment of the present invention is directed to the use of lacritin to treat Dry Eye and other disorders requiring the wetting of the eye.
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patent: WO 98/27205 (1998-06-01), None
patent: WO 98/35229 (1998-08-01), None
Rudinger, InPeptide Hormones, J. R. Parsons, ed., University Park Press, Baltimore, pp. 1-7, 1976.
Lumsden, A.J., Dickinson, D.P., and Laurie, G.W., (1998). “Paired oligonucleotide screening for ‘BM 180’ in a human lacrimal gland cDNA library: Clome HL-2”., Am. Society for Cell Biology Annual Meeting.
Sanghi, S., and Laurie, G.W., (1999). “cDNA Cloning and Expression of ‘lacritin’, a novel secreted glycoprotein of the lacrimal gland”., Am. Society for Cell Biology Annual Meeting.
Sanghi, S., Kumar, R. Walton, S., and Laurie, G.W., (2000).“Quantitation of rat lacrimal secretion: novel sandwich ELISA with high sensitivity”., Exp. Eye Res., p. 651-658.
Rudinger, J., ““Characteristics of the amino acids as components of a peptide hormone sequence”,” Peptide Hormones, University Park Press (Baltimore), (June 14, 1976).
Laurie Gordon W.
Lumsden Angela J.
Rajesh Kumar
Sanghi Sandhya
Chan Christina
Gucker Stephen
Sparks Rodney L.
University of Virginia Patent Foundation
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